Calbindin immunoreactivity is a characteristic of enterochromaffin-like cells (ECL cells) of the human stomach |
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| Authors: | J B Furness R T A Padbury K G Baimbridge J M Skinner D E M Lawson |
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| Institution: | (1) Department of Anatomy and Histology, School of Medicine, Flinders University of South Australia, 5042 Bedford Park, S.A., Australia;(2) Department of Surgery, Flinders University, 5042 Bedford Park, S.A., Australia;(3) Department of Histopathology, Flinders University, 5042 Bedford Park, S.A., Australia;(4) Department of Physiology, University of British Columbia, Canada;(5) Institute of Animal Physiology, Babraham, Cambridge, UK |
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| Abstract: | Summary Immunoreactivity for the calicium binding protein, calbinding D28k has been localized in enterochromaffin-like (ECL) cells of the human stomach. The reactivity was observed with three different antisera, raised against bovine brain, primate brain, and chicken intestinal calbindin. The ECL cells were closed endocrine cells located at the bases of the oxyntic glands. They were not found in other regions of the stomach. No other gastric endocrine cells were reactive with these antisera. |
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