Fermentation of Bacillus thuringiensis for exotoxin production: Process analysis study |
| |
Authors: | Andrea Holmberg Risto Sievnen Gunnel Carlberg |
| |
Institution: | Andrea Holmberg,Risto Sievänen,Gunnel Carlberg |
| |
Abstract: | The exotoxin produced by certain serotypes of Bacillus thuringiensis was used as a means of microbiological control of the larval development of flies. The optimal batch cultivation conditions with respect to pH, temperature, aeration, agitation, and initial concentration of growth-limiting substrate were determined. A dynamic model describing the process was designed and fitted to the experimental data. The application of a method for estimating exotoxin and bacterial concentrations from on-line measurable quantities such as oxygen consumption and heat production is presented. |
| |
Keywords: | |
|
|