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Viral ion channel proteins in model membranes: a comparative study by X-ray reflectivity |
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| Authors: | Z. Khattari E. Arbely I. T. Arkin T. Salditt |
| Affiliation: | 1. Institut für R?ntgenphysik, Universit?t G?ttingen Friedrich-Hund-Platz 1, 37077, G?ttingen, Germany 2. The Alexander Silberman Institute of Life Sciences, Department of Biological Chemistry, The Hebrew University of Jerusalem, Givat-Ram, Jerusalem, 91904, Israel |
| Abstract: | We have investigated the effect of the transmembrane domain of three viral ion channel proteins on the lipid bilayer structure by X-ray reflectivity and scattering from oriented planar bilayers. The proteins show a similar effect on the lipid bilayer structural parameters: an increase in the lipid bilayer hydrophobic core, a decrease in the amplitude of the vertical density profile and a systematic change in the ordering of the acyl chains as a function of protein-to-lipid ratio. These results are discussed in a comparative view. |
| Keywords: | Viral ion channel proteins Lipid bilayer Acyl chain correlation X-ray reflectivity |
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