Circadian Rhythm in Pineal Methionine S-Adenosyltransferase |
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Authors: | Ras B. Guchhait rew A. Monjan |
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Affiliation: | Department of Epidemiology, The Johns Hopkins University, School of Hygiene and Public Health, Baltimore, Maryland, U.S.A. |
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Abstract: | Abstract: The circadian rhythm of methionine S -adenosyltransferase, which catalyzes the formation of S -adenosylmethionine, a cosubstrate for melatonin in the pineal gland, follows the pattern of hydroxyindole- O -methyltransferase. Around the middle of the dark period, methionine S -adenosyltransferase and hydroxyindole- O -methyltransferase appear to be elevated by 2.5- and 1.5-fold, respectively, and tend to fall back during the light period. |
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Keywords: | Circadian rhythm Hydroxyindole-O-methyltransferase Melatonin Methionine S-adenosyltransferase S-Adenosylmethionine |
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