| CD4+CD25+调节性T细胞的外周维持 |
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| 引用本文： | 徐林,熊思东.CD4+CD25+调节性T细胞的外周维持[J].细胞生物学杂志,2007,29(5):629-632. |
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| 作者姓名： | 徐林 熊思东 |
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| 作者单位： | 复旦大学免疫生物研究所 上海医学院免疫学系，复旦大学免疫生物研究所，上海医学院免疫学系，上海200032，上海200032 |
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| 摘 要： | CD4 CD25 调节性T细胞作为一种抑制性T细胞功能亚群,在维持机体的免疫自稳和免疫耐受方面发挥了关键作用。该作用的发挥与其外周细胞库的维持密切相关。新近的研究显示CD4 CD25 调节性T细胞主要通过两种机制来维持其外周细胞库,一些功能分子参与其中。
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| 关 键 词： | 免疫自稳 CD4 CD25 调节性T细胞 记忆性T细胞 |
| 修稿时间： | 2007-03-24 |
Peripheral Homeostasis of CD4+CD25+ Regulatory T Cells |
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| Lin Xu,Si-Dong Xiong.Peripheral Homeostasis of CD4+CD25+ Regulatory T Cells[J].Chinese Journal of Cell Biology,2007,29(5):629-632. |
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| Authors: | Lin Xu Si-Dong Xiong |
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| Institution: | Institute for lmmunobiology, Department of Immunology of Shanghai Medical College, Fudan University, Shanghai 200032, China |
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| Abstract: | CD4 CD25 regulatory T cells, a functional subset of inhibitory T cells, play a crucial role in the maintenance of immune homeostasis and immune tolerance. These functions are closely correlated to peripheral homeostasis of CD4 CD25 regulatory T cells. Recent evidence showed that there are two ways that could contrib-ute to the peripheral homeostasis of CD4 CD25 regulatory T cells, in which some functional molecules may be involved. |
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| Keywords: | immune homeostasis CD4 CD25 regulatory T cells memory T cells |
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