Determining the Presence of Superantigens in Coagulase Negative Staphylococci from Humans |
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| Authors: | Christopher S Stach Bao G Vu Patrick M Schlievert |
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| Institution: | Department of Microbiology, University of Iowa Carver College of Medicine, Iowa City, Iowa, United States of America.; Universitätsklinikum Hamburg-Eppendorf, GERMANY, |
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| Abstract: | Superantigens (SAgs) are important virulence factors in S. aureus. Recent studies identified their presence in animal coagulase-negative staphylococci (CNS). The emergence of human-associated SAg+ CNS would mark a prodigious shift in virulence capabilities. We examined CNS isolates from healthy human nares and diseased individuals, and determined that no known SAgs were present. |
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