| 铁死亡调控机制与肿瘤发生与治疗的研究进展 |
| |
| 引用本文： | 郭仪青,陈广. 铁死亡调控机制与肿瘤发生与治疗的研究进展[J]. 生理科学进展, 2019, 0(2): 88-93 |
| |
| 作者姓名： | 郭仪青 陈广 |
| |
| 作者单位： | 华中科技大学同济医学院附属同济医院;华中科技大学同济医学院附属同济医院中西医结合科 |
| |
| 基金项目： | 国家自然科学基金(81774259;81403243)资助课题 |
| |
| 摘 要： | 铁死亡是一种不同于凋亡与坏死的新细胞死亡方式,它与铁代谢及氧化损伤具有高度相关性,并以胞质和脂质的活性氧明显增多、线粒体体积变小以及膜密度增厚为死亡标志。近来研究者发现铁死亡在许多疾病中发挥着重要的作用。本文通过对铁死亡及其机制的总结分析,阐明铁死亡及其机制在肿瘤发生与治疗中相关研究和最新进展。
|
| 关 键 词： | 铁死亡 铁代谢 肿瘤 脂质过氧化 诱导剂 抑制剂 |
Research on Regulatory Mechanism of Ferroptosis and Progress in Tumorigenesis and Therapy |
| |
| GUO Yi-Qing,CHEN Guang. Research on Regulatory Mechanism of Ferroptosis and Progress in Tumorigenesis and Therapy[J]. Progress in Physiological Sciences, 2019, 0(2): 88-93 |
| |
| Authors: | GUO Yi-Qing CHEN Guang |
| |
| Affiliation: | (Tongji Hospital, Tongji Medical College, Huazhong niversity of Science and Technology, Wuhan 430030, China;Department of Integrated Traditional Chinese and Western Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China) |
| |
| Abstract: | GUO Yi-Qing;CHEN Guang(Tongji Hospital, Tongji Medical College, Huazhong niversity of Science and Technology, Wuhan 430030, China;Department of Integrated Traditional Chinese and Western Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China) |
| |
| Keywords: | ferroptosis iron metabolism tumors lipid peroxidation inducers inhibitors |
| 本文献已被 CNKI 维普 等数据库收录！ |
|
