Status of the search for a major genetic locus for affective disorder in the Old Order Amish |
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| Authors: | Andrew J. Pakstis Judith R. Kidd Carmela M. Castiglione Kenneth K. Kidd |
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| Affiliation: | (1) Department of Human Genetics, Yale University School of Medicine, 333 Cedar Street, 06510 New Haven, CT, USA |
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| Abstract: | Summary We have resumed the search for an autosomal linkage with affective disorder in the Old Order Amish and report the pairwise linkage results after screening 185 marked loci. No positive evidence of genetic linkage was found, and we estimate that roughly 23% of the autosomal genome has been excluded from linkage. |
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