低氧对雄性高原鼠兔性腺的影响

在人工模拟低氧环境下（低压舱模拟５０００ｍ和７０００ｍ海拔高度），低氧暴露２４ｈ和７ｄ，观察低氧对受试动物性腺的影响。结果表明，急性低氧２４ｈ，高原鼠兔血浆雌二醇（Ｅ２）明显升高；低氧暴露７ｄ，高原鼠兔血浆Ｅ２仍维持一较高水平；５０００ｍ低氧暴露７ｄ，其睾丸指数无明显变化，７０００ｍ时却有所降低。同等条件下，大鼠睾丸指数明显增高；５０００ｍ和７０００ｍ低氧暴露７ｄ对高原鼠兔睾丸组织形态无明显影响，然而，大鼠曲细精管间隙增大，且曲细精管内各级细胞排列紊乱。低氧环境下，高原鼠兔雄体血浆Ｅ２增高，可能是其低氧适应的特征之一

EFFECT OF HYPOXIA ON THE SEX GLAND OF MALE PLATEAU PIKA

Effects of hypoxia on the sex gland of male plateau pika (Ochotona curzoniae) and rat were carried out by simulated different altitude (5 000 m and 7 000 m) in the well ventilated hypobaric pressure chamber for 24 h and 7 d, comparing with that at 2 300 m of altitude.The experiment shows: the plasma estrogen(E 2) level of male plateau pika increased obviously at 5 000 m and 7 000 m altitude for 24 h and 7 d. The ratio of testis to body weights in plateau pika was no change at 5 000 m of altitude but decreased at 7 000 m for hypoxia 7 d, by contrary, that of rat increased significantly at the same condition.The testicular histomorphology of plateau pika kept unchangeable at all altitude simulated for 7 d. These suggest that E 2 may play a role in an adaptation to hypoxia in Ochotona curzoniae .