真菌草酸的代谢和作用研究进展

草酸(oxalic acid)是一种重要的生物代谢产物,广泛分布于植物、动物和微生物中,在不同的生命体中发挥重要功能.本文回顾了国内外关于真菌草酸的相关研究进展.许多真菌能够分泌草酸,包括植物病原真菌、食药用真菌及工业真菌等.草酸作为一种简单的二元羧酸,在真菌中主要通过三羧酸循环途径、乙醛酸循环途径和草酰乙酸途径合成....

Research progress on metabolism and function of fungal oxalic acid

Oxalic acid, a metabolite with important functions, is ubiquitous in plants, animals, and microorganisms. Many fungi have been reported to be able to secrete oxalic acid, including plant pathogenic fungi, edible and medicinal fungi, and industrial fungi. Oxalic acid as a simple dicarboxylic acid is synthesized in fungi mainly through tricarboxylic acid cycle, glyoxylate cycle, and oxaloacetate pathway. Oxalic acid is an important biological factor produced by fungi, which not only affects the growth and development of fungi but also plays a role in fungus-plant interactions through toxin action, acidification of host plant tissue environment, participation in cell wall degradation, and induction of reactive oxygen species production. Therefore, it is essential in the life cycle and infection cycle of fungi. This paper reviews the properties and metabolism of oxalic acid, the oxalic acid-producing fungal species, the role of oxalic acid and oxalic acid-related genes in these species. Furthermore, we put forward the questions to be solved in the related research, aiming to provide scientific references for the utilization of the fungal resources producing oxalic acid and research ideas for the integrated management of plant fungal diseases.