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Synthesis,in vitro biological activity and docking of new analogs of BIM-23052 containing unnatural amino acids |
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| Authors: | Naydenova Emilia Wesselinova Diana Staykova Svetlana Danalev Dancho Dzimbova Tatyana |
| Institution: | 1.Department of Organic Chemistry, University of Chemical Technology and Metallurgy, Blvd. 8 Kl. Ohridski, 1756, Sofia, Bulgaria ;2.Institute of General and Comparative Pathology, Bulgarian Academy of Sciences, Acad. G. Bonchev Street, Bl. 25, 1113, Sofia, Bulgaria ;3.Institute of Molecular Biology “Roumen Tsanev”, Bulgarian Academy of Sciences, Acad. G. Bonchev Street, Bl. 21, 1113, Sofia, Bulgaria ;4.South-West University “Neofit Rilski”, 66 Ivan Mihaylov Str, 2700, Blagoevgrad, Bulgaria ; |
| Abstract: | Amino Acids - Somatostatin (SST) is an endogenous cyclic tetradecapeptide hormone that exerts multiple biological activities via a family of five receptors. BIM-23052 (DC-23-99)... |
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