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Ablation of PRDM16 and Beige Adipose Causes Metabolic Dysfunction and a Subcutaneous to Visceral Fat Switch
Affiliation:1. Dana-Farber Cancer Institute and Department of Cell Biology, Harvard Medical School, Boston, MA 02215, USA;2. Cardiovascular Division, Department of Medicine, Brigham and Women’s Hospital, Boston, MA 02115, USA;3. Department of Experimental and Clinical Medicine, Università Politecnica delle Marche, Ancona 60020, Italy;4. Division of Immunology, Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA;5. Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN 37232, USA;6. Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06519, USA;7. Department of Cellular and Molecular Physiology and Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06519, USA;8. UCSF Diabetes Center and Department of Cell and Tissue Biology, University of California San Francisco, San Francisco, CA 94143, USA;9. Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA
Abstract:
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