Identification of Staphylococcus xylosus isolated from C57BL/6J-Nos2(tm1Lau) mice with dermatitis |
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| Authors: | Won Young Suk Kwon Hyo Jung Oh Goo Taeg Kim Bang Hyun Lee Chul Ho Park Yong Ho Hyun Byung Hwa Choi Yang Kyu |
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| Institution: | Department of Microbiology, College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National University, Suwon, Korea. |
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| Abstract: | Coagulase negative staphylococci (CNS) are significant pathogens, particularly in medical device related infections and in immunocompromised patients. Five CNS strains were isolated from 5 NOS2 knockout mice with dermatitis. Histologically, granulomatous dermatitis was found in the skin around the ear with epidermal ulceration. Dermal lesions included pustules, necrosis, and accumulations of neutrophils and macrophages. Isolates of the bacterial strains were identified to be Staphylococcus xylosus by the API STAPH kit and 16S-23S intergenic transcribed spacer-PCR. These results demonstrate the potential of this organism to be an opportunistic pathogen in immunocompromised mice. |
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| Keywords: | staphylococcus xylosus ITS‐PCR granulomatous dermatitis |
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