Minireview: Expression and Function of Golli Protein in Immune System

In this minireview, the author briefly reviews the development of our understanding on the immunological function of golli proteins. In the immune system, in addition to serving as autoantigens, golli proteins have been recently found to regulate T-cell activation directly, thus modulating EAE induction. The evidence that golli proteins function as signal molecules is summarized. Special issue dedicated to Dr. Anthony T. Campagnoni and Celia W. Campagnoni.