Preparation of 4,15-diacetoxyscirpenol from cultures of Fusarium sambucinum NRRL 13495. |
| |
| Authors: | K E Richardson and P B Hamilton |
| |
| Abstract: | Filtrates of Fusarium sambucinum NRRL 13495 grown in a stagnant culture for 9 days contained up to 458 +/- 60 (mean +/- standard error; n = 3) mg of 4,15-diacetoxyscirpenol per liter depending on culture conditions. Extraction with ethyl acetate, chromatography on a column of silica gel, and crystallization from mixtures of ethyl acetate and hexane provided pure material in 96% yield. |
| |
| Keywords: | |
|
|
