The lantibiotic mersacidin is a strong inducer of the cell wall stress response of <Emphasis Type="Italic">Staphylococcus aureus</Emphasis> |
| |
Authors: | Peter Sass Andrea Jansen Christiane Szekat Vera Sass Hans-Georg Sahl Gabriele Bierbaum |
| |
Institution: | (1) Institute of Medical Microbiology, Immunology and Parasitology (IMMIP), University of Bonn, Sigmund-Freud-Str. 25, 53105 Bonn, Germany |
| |
Abstract: | Background The lantibiotic mersacidin is an antimicrobial peptide of 20 amino acids that is ribosomally produced by Bacillus sp. strain HIL Y-85,54728. Mersacidin acts by complexing the sugar phosphate head group of the peptidoglycan precursor lipid
II, thereby inhibiting the transglycosylation reaction of peptidoglycan biosynthesis. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|