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Epigenetic dynamics in immunity and autoimmunity
Affiliation:1. Department of Dermatology and Epigenetic Research Center, Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China;2. Division of Rheumatology, Allergy, and Clinical Immunology, University of California at Davis, Davis, USA;1. Department of Dermatology, Hunan Key Laboratory of Medical Epigenomics, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410011, China;2. Department of Medical Cosmetology, The First Affiliated Hospital of University of South China, Hengyang 421001, China;1. Department of Dermatology and Epigenetic Research Center, Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, PR China;2. Clinical Medical Research Center, the Second Clinical Medical College of Jinan University (Shenzhen People''s Hospital), Shenzhen, Guangdong 518020, PR China;3. Division of Nephrology, Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China;1. Hunan Key Laboratory of Medical Epigenomics, Department of Dermatology, Second Xiangya Hospital, Central South University, Changsha, Hunan, China;2. Changsha Blood Center, Changsha, Hunan, China;3. Clinical Medical Research Center, the Second Clinical Medical College of Jinan University (Shenzhen People’s Hospital), Shenzhen, Guangdong, China;4. Division of Nephrology, Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China;1. Department of Dermatology, Second Xiangya Hospital, Central South University, Changsha, Hunan, China;2. Hunan Key Laboratory of Medical Epigenomics, Changsha, Hunan, China
Abstract:
Keywords:Epigenetic dynamics  Immune system  Autoimmune diseases  DNA methylation  Histone modifications  DNMT"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0035"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  DNA methyltransferase  TET"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0045"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  ten-eleven translocation  AID/AICDA"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0055"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  activation-induced cytidine deaminase  APOBEC"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0065"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Apolipoprotein B mRNA editing enzyme  BER"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0075"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  base excision repair  MBD4"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0085"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  methyl-CpG binding domain protein 4  HATs"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0095"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  histone acetyltransferases  HDAC"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0105"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  histone deacetylase  HMT"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0115"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  histone methyltransferase  5mC"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0125"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  5-methylcytosine  5hmC"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0135"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  5-hydroxymethylcytosine  GC"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0145"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  germinal center  DC"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0155"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  dendritic cell  SHM"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0165"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  somatic hypermutation  CSR"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0175"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  class switch recombination  Blimp-1"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0185"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  B lymphocyte-induced maturation protein-1  Treg"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0195"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  regulatory T  NFAT"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0205"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  nuclear factor of activated T-cells  TSDR"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0215"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Treg-specific demethylated region  PDCD1"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0225"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  programmed cell death 1  Prf1"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0235"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Perforin  Gzmb"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0245"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Granzyme B  CTL"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0255"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  cytotoxic T cell  EBF1"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0265"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  early B cell factor1  Pax5"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0275"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Paired box protein  TSA"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0285"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Trichostatin A  SLE"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0295"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  systemic lupus erythematosus  RA"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0305"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  rheumatoid arthritis  MS"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0315"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  multiple sclerosis  T1D"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0325"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  type 1 diabetes mellitus  ERK"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0335"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  extracellular regulated protein kinases  PBMC"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0345"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  peripheral blood mononuclear cell  PAD2"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0355"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  peptidylarginine deiminase 2  IGFBP-1"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0365"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  insulin-like growth factor-binding protein 1  LPS"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0375"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  lipopolysaccharide
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