Enantiospecific synthesis and insect feeding activity of sulfur-containing cyclitols |
| |
Authors: | Bellomo Ana Camarano Soledad Rossini Carmen Gonzalez David |
| |
Affiliation: | a Laboratorio de Síntesis Orgánica, D.Q.O, Fac. de Química, Univ. de la República, C.C. 1157 Montevideo, Uruguay b Laboratorio de Ecología Química, D.Q.O.—DepBio, Fac. de Química, Univ. de la República, C.C. 1157 Montevideo, Uruguay |
| |
Abstract: | The first syntheses of two deoxythiocyanocyclitols (4-deoxy-4-thiocyano-l-chiro-inositol and deoxythiocyanoconduritol F) and two deoxysulfonylcyclitol acetals are reported by a chemoenzymatic enantioselective route. The compounds were prepared by a sequence of enzymatic and ruthenium-catalyzed dihydroxylations, and the results were studied regarding reaction conditions and co-catalyst for different derivatives. The new compounds were included in a minilibrary of deoxygenated cyclitols and evaluated for their capacity to influence the feeding behavior of Epilachna paenulata (Coleoptera: Coccinellidae), a common pest of the Curcubitaceae crops. |
| |
Keywords: | Thiocyanodeoxycyclitol Dihydroxylation Insect feeding behavior |
本文献已被 ScienceDirect PubMed 等数据库收录! |
|