Analysis of Recombination in Campylobacter jejuni from MLST Population Data |
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| Authors: | Paul Fearnhead Nick G.C. Smith Mishele Barrigas Andrew Fox Nigel French |
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| Affiliation: | (1) Department of Mathematics and Statistics, Lancaster University, Lancaster, LA1 4YF, UK;(2) University of Staffordshire, Stafford, UK;(3) Health Protection Agency North West, Manchester Medical Microbiology Partnership, Manchester Royal Infirmary, Manchester, UK;(4) Institute of Veterinary, Animal and Biomedical Sciences, Massey University, Palmerston North, New Zealand |
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| Abstract: | ![]()
We analyze recombination in C. jejuni using MLST data from isolates taken from wild birds, cattle, wild rabbits, and water in a 100-km2 study region in Cheshire, UK. We use a recent approximate likelihood method for inference, based on combining likelihood information from all pairs of segregating (polymorphic) sites in the data. We find substantial evidence for recombination, but only for recombination with short tract lengths, of around 225–750 bp. We estimate that the rate of recombination is of a similar magnitude to the rate of mutation.[Reviewing Editor: Dr. Magnus Nordborg] |
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| Keywords: | Bacteria Campylobacter Helicobacter MLST Recombination rate Recombination tract length |
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