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Proton Transport Mechanism of Bacteriorhodopsin as Revealed by Site-Specific Mutagenesis and Protein Sequence Variability
Authors:L. S. Brown
Affiliation:(1) Department of Physiology and Biophysics, University of California, Irvine, California 92697, USA
Abstract:
A large share of the current ideas about the mechanism of proton transport by bacteriorhodopsin has emerged from studies of site-specific mutants. This review is an attempt to check some of these ideas against the natural variability in the primary structure of the protein.
Keywords:bacteriorhodopsin  halobacteria  mutations  photocycle  proton transport  conserved residues
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