The synthesis of cartilage collagen by rabbit and human chondrocytes in primary cell culture |
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Authors: | Fred H Schindler Marsha A Ose Michael Solursh |
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Institution: | (1) Department of Zoology, University of Iowa, 52242 Iowa City, Iowa |
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Abstract: | Summary This report describes a method for preparing primary cell cultures of differentiated rabbit sternal and human vertebral cartilage
cells. These cell cultures were shown to synthesize primarily α1 chains, which is taken to mean that at least 82% of the collagen
produced is cartilage specific collagen (type II).
This work was supported in part by grant HD-05505 from NIH. |
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Keywords: | mammalian cartilage cell cultures collagen synthesis differentiation chondrocytes |
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