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免疫器官辐射损伤与防护的研究进展
引用本文:贺许良卢先州陈枚叶浩周振华张树友. 免疫器官辐射损伤与防护的研究进展[J]. 现代生物医学进展, 2014, 14(5): 997-200
作者姓名:贺许良卢先州陈枚叶浩周振华张树友
作者单位:南华大学附属南华医院普外科,湖南衡阳4210021
基金项目:湖南省科技厅基金项目(2011FJ3002)
摘    要:
随着社会的发展,核医学技术、放射医学技术的持续发展及广泛应用,当今世界核武器、核电站泄漏等事故偶有发生,以及人类现代生活和工作中广泛应用各种高科技电子产品,各类肿瘤病人接受放疗,人类生活圈四周充满的是多种放射线。电离辐射不仅对人类生命和财产造成损害,而且也对生理和心理造成严重创伤。因此对辐射的防治极为重要,加强对辐射的损伤机制及防护研究具有十分重要的现实意义。辐射导致的免疫损伤及其引发的免疫功能障碍,是核辐射、放射治疗和放射性核事故患者最常见的并发症,死亡率极高,至今仍是临床上亟待解决的难题。本文探讨了辐射免疫损伤效应和机理研究方面需要解决的问题,以及提出了进一步研究辐射免疫损伤防护措施的切入点。

关 键 词:免疫损伤  电离辐射  脾脏  辐射防护

Research Progress of Immune Organs Radiation Damageand Protect
HE Xu-liang,LU Xian-zhou,CHEN Mei,YE Hao,ZHOU Zhen-hu,ZHANG Shu-you. Research Progress of Immune Organs Radiation Damageand Protect[J]. Progress in Modern Biomedicine, 2014, 14(5): 997-200
Authors:HE Xu-liang  LU Xian-zhou  CHEN Mei  YE Hao  ZHOU Zhen-hu  ZHANG Shu-you
Affiliation:(Department of General Surgery,Attliated Nanhua Hospital of Nanhua University, Hengyang, Hunan, 421002, China)
Abstract:
With the social development, nuclear medicine technology and radiology technology continuous development and wide application. In today's world nuclear weapons, nuclear power plant leaks and other accidents occasionally occur, as well as human life and work of modem extensive application of various high-tech electronic products, various cancer patients receiving radiotherapy, the human living area is filled with a variety of much radiation. Ionizing radiation not only to human life and property damage, but also to cause serious physical and psychological trauma. Therefore, prevention and treatment of radiation is extremely important to strengthen the mechanisms of injury and radiation protection research has a very important practical significance. Radiation-induced immune injury and resulting immune dysfunction, nuclear radiation, radiation therapy and radioactive nuclear accident patients with the most common complication, high mortality rate, is still clinically urgent problem. This paper discusses the radiation damage effects and mechanism of immunity need to solve the problems and make recommendations for further study of radiation protection measures immune injury to start.
Keywords:Immune damage  Ionizing radiation  Spleen  Radiation Protection
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