PET/CT和超声弹性成像在乳腺癌诊断中的价值对比分析

目的:探讨PET/CT和超声弹性成像(UE)在乳腺癌诊断中的价值。方法:回顾性分析2011年1月至2012年5月在我院确诊的173例乳腺患者的临床资料,所有患者均行PET/CT和UE检查。依据病理组织活检和临床随访分别评价PET/CT和UE对乳腺癌诊断的灵敏性、特异性、准确性,并比较两者的结果。结果:PET/CT和UE诊断乳腺癌的灵敏性分别为98.8%和81.3%;特异性分别为84.3%和97.2%;准确性分别为90.7%和90.2%;两种方法联合检测诊断乳腺癌的灵敏性、特异性、准确性分别为98.8%、98.1%、98.4%,UE检测乳腺癌的敏感性明显低于PET/CT及PET/CT+UE,PET/CT检测乳腺癌的特异性明显低于UE及PET/CT+UE,PET/CT+UE诊断乳腺癌的准确性显著提高(P0.05)。结论:PET/CT和超声弹性成像在乳腺癌诊断中均有较高的应用价值,各有优缺点,二者联合检测可提高乳腺癌诊断的准确率。

Comparative Analysis of the Clinical Value of PET/CT and Ultrasound Elastography in the Diagnosis of Breast Cancer

Objective： To investigate the clinical value of PET/CT and ultrasound elastography （UE） in the diagnosis of breast cancer. Methods： A retrospective analysis of 173 cases of breast cancer diagnosed from January 2011 to May 2012 was performed, all the patients underwent PET/CT and UE examination. The sensitivity, specificity and accuracy of PET/CT and UE in the diagnosis of breast cancer was analyzed according to the results of pathological tissue biopsy. Results： The sensitivity of PET/CT and UE were respectively 98.8% and 81.3%; the specificity of were respectively 84.3% and 97.2%; while the accuracy were respectively 90.7% and 90.2%; combi- nation of the two methods, the sensitivity, specificity, and accuracy were respectively 98.8%, 98.1%, 98.4%~ The sensitivity of UE was significantly lower than those of PET/CT and PET/CT＋UE, the specificity of PET/CT was significantly lower than those of UE and PET/ CT＋UE, while the accuracy of PET/CT＋UE was significantly higher than those of PET/CT and UE （P〈0.05）. Conclusion： PET/CT and ultrasound elastography both possessed advantages and disadvantages in the diagnosis of breast cancer, the combination of which improved the accuracy of the diagnosis of breast cancer.