One‐step synthesis of nitrogen,boron co‐doped fluorescent carbon nanoparticles for glucose detection |
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| Authors: | Meijuan Liang Yi Ren Haijuan Zhang Yunxia Ma Xiaoying Niu Xingguo Chen |
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| Institution: | 1. State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, China;2. Department of Chemistry, Lanzhou University, Lanzhou, China;3. Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province, Lanzhou, China |
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| Abstract: | Heteroatom‐doped carbon nanoparticles (CNPs) have attracted considerable attention due to an effective improvement in their intrinsic properties. Here, a facile and simple synthesis of nitrogen, boron co‐doped carbon nanoparticles (NB‐CNPs) from a sole precursor, 3‐aminophenylboronic acid, was performed via a one‐step solid‐phase approach. Because of the presence of boronic acid, NB‐CNPs can be used directly as a fluorescent probe for glucose. Based on a boronic acid‐triggered specific reaction, we developed a simple NB‐CNP probe without surface modification for the detection of glucose. When glucose was introduced, the fluorescence of NB‐CNPs was suppressed through a surface‐quenching states mechanism. Obvious fluorescence quenching allowed the highly sensitive determination of glucose with a limit of detection of 1.8 μM. Moreover, the proposed method has been successfully used to detect glucose in urine from people with diabetes, suggesting potential application in sensing glucose. |
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| Keywords: | glucose NB‐CNPs people with diabetes solid phase |
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