Highly luminescent S,N co‐doped carbon quantum dots‐sensitized chemiluminescence on luminol–H2O2 system for the determination of ranitidine |
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Authors: | Jianqiu Chen Juan Shu Jiao Chen Zhiran Cao An Xiao Zhengyu Yan |
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Affiliation: | 1. School of Science, China Pharmaceutical University, Nanjing, ChinaJianqiu Chen and Juan Shu contributed equally to this work.;2. School of Science, China Pharmaceutical University, Nanjing, China |
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Abstract: | S,N co‐doped carbon quantum dots (N,S‐CQDs) with super high quantum yield (79%) were prepared by the hydrothermal method and characterized by transmission electron microscopy, photoluminescence, UV–Vis spectroscopy and Fourier transformed infrared spectroscopy. N,S‐CQDs can enhance the chemiluminescence intensity of a luminol–H2O2 system. The possible mechanism of the luminol–H2O2–(N,S‐CQDs) was illustrated by using chemiluminescence, photoluminescence and ultraviolet analysis. Ranitidine can quench the chemiluminescence intensity of a luminol–H2O2–N,S‐CQDs system. So, a novel flow‐injection chemiluminescence method was designed to determine ranitidine within a linear range of 0.5–50 μg ml?1 and a detection limit of 0.12 μg ml?1. The method shows promising application prospects. |
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Keywords: | chemiluminescence flow‐injection ranitidine S,N co‐doped carbon quantum dots |
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