SIGNAL SCAN: a computer program that scans DNA sequences for eukaryotic transcriptional elements

SIGNAL SCAN is a program that has been developed to aid themolecular biologist in determining what eukaryotic transcriptionfactor elements (and other significant elements) may exist ina DNA sequence under investigation. The program usesflatfiledatabases of these elements. SIGNAL SCAN is most useful foranalyzing mammalian sequences due to the prevalence of mammalianelements in the database. Elements not found in the SIGNAL SCANdatabase may be entered by the user. SIGNAL SCAN uses both specificsequence elements derived from biochemical characterizationand elements from derived consensus sequences to match againsta user input DNA sequence. While any DNA sequence element matchingan element in the SIGNAL SCAN database will be reported by theprogram, the determination of the biological relevance of theelement is left up to the investigator. Received on June 15, 1990; accepted on November 11, 1990