慢性乙型肝炎及肝硬化患者幽门螺杆菌感染的临床特征分析

目的:分析慢性乙型肝炎及肝硬化患者幽门螺杆菌感染的临床特征。方法:选取2013年5月到2014年5月我院收治的胃镜检查患者58例,其中肝硬化患者17例(肝硬化组),慢性乙型肝炎患者22例(慢性乙型肝炎组),普通患者19例(普通组),根据肝硬化门脉高压的严重程度将患者分为轻型(5例)、中型(7例)和重型(5例),比较各组幽门螺杆菌的感染情况。结果:肝硬化组、慢性乙型肝炎组及普通组幽门螺杆菌感染率分别为23.5%,22.7%,21.1%,三组比较差异无统计学意义(x2=2.872,P=0.072);肝硬化轻、中、重患者幽门螺杆菌感染率分别为20.0%、28.6%、20.0%,三者比较无统计学意义(x2=1.892,P=0.082)。结论:慢性乙型肝炎、肝硬化及普通患者幽门螺杆菌感染情况相似,且幽门螺杆菌感染对肝硬化门静脉高压无影响。

Patients with Chronic Hepatitis B and Hepatocirrhosis: Clinical Characteristics of Helicobacter Pylori Infection

Objective:To analyze the clinical characteristics of Helicobacter pylori infection in patients with chronic hepatitis B and hepatocirrhosis.Methods:A total of 58 patients, who underwent stomachoscopy in Hainan Provincial People''s Hospital from May 2013 to May 2014, were selected, including 17 patients with hepatocirrhosis (hepatocirrhosis group), 22 patients with chronic hepatitis B (chronic hepatitis B group), and 19 other patients (normal group). The hepatocirrhosis group was divided into mild group (n=5), medium group(n=7) and severe group(n=5) according to the severity of portal hypertension Then clinical characteristics of Helicobacter pylori infection among the three groups were compared.Results:The Helibacter pylori infection rate in hepatocirrhosis group, chronic hepatitis B group and normal group were 23.5%, 22.7%, and 21.1% respectively, there was no significant differences among the three groups (x2=2.872, P=0.072). The Helicobacter pylori infection rate in mile, medium and severe groups were 20.0%(1/5), 28.6%(2/7), and 20.0% (1/5) respectively, there was no significant differences among the three groups (x2=1.892, P=0.082).Conclusion:The chronic hepatitis B, hepatocirrhosis and other ordinary patients have a similar status of infection, and helicobacter pylori infection has no impact on portal hypertension of hepatocirrhosis.