不同子宫手术方案对生育期妇女卵巢功能的影响

目的:研究不同子宫手术方案对生育期妇女卵巢功能的影响。方法:随机选取自2014年1月至2015年4月于我院进行手术治疗的200例生育期妇女作为研究对象。针对所有患者在术前1d及术后6个月分别进行静脉采血5 m L,比较患者手术前后促卵泡激素(FSH)及雌二醇(E2)水平,不同年龄与手术方案患者手术前后血清抗苗勒氏管激素(AMH)的水平。结果:术后患者的FSH及E2水平与术前比较,差异无统计学意义(P0.05)。40岁者手术后的血清AMH水平显著低于术前,差异有统计学意义(P0.05)。在手术方式中,子宫切除术(子宫全切及广泛性子宫切除)后患者血清AMH显著低于术前的水平,差异有统计学意义(P0.05)。在手术途径中,腹腔镜辅助子宫切除术后患者血清AMH显著低于术前的水平,差异有统计学意义(P0.05)。结论:≥40岁患者在接受子宫手术时可能会影响其卵巢储备功能,而子宫全切、广泛性子宫切除以及腹腔镜辅助子宫切除术对患者术后卵巢功能影响更大。

Effect of Different Surgery Schemes on Ovarian Function of Women in Reproductive Stage

Objective:To study the effect of different surgery schemes on ovarian function of women in reproductive stage.Methods:A total of 200 women, who underwent surgical treatment in Xinxiang Central Hospital of Henan Province from January 2014 to April 2015, were randomly selected as the research subjects. All the patients were collected 5 mL venous blood 1 d before surgery and 6 months after surgery. The levels of follicle stimulating hormone (FSH) and estradiol (E2) before and after surgery, and the levels of serum anti-mullerian hormone(AMH) of the patients in different age and surgery plan were compared.Results:There were no significant differences in the levels of FSH and E2 of the patients between before surgery and after surgery(P>0.05). The level of serum AMH in the patients aged more than 40 after surgery was significantly lower than before surgery, and the difference was statistically significant(P<0. 05). In the surgery mode, the levels of serum AMH in the patients after hysterectomy (hysterectomy and extensive hysterectomy) were significantly lower than before surgery, and the difference was statistically significant(P<0.05). In the surgical method, the level of serum AMH in the patients after hysterectomy with the assistance of laparoscopic was significantly lower than before surgery, the difference was statistically significant(P<0.05).Conclusion:The ovarian reserve functions of the patients aged 40 and over may be influenced when accepted uterine surgery; hysterectomy, extensive hysterectomy and hysterectomy with the assistance of laparoscopic patients may seriously influence the ovarian reserve functions of the patients after surgery.