Infections caused by RSV among children and adults during two epidemic seasons |
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Authors: | Pancer Katarzyna Cia?ka Agnieszka Gut W?odzimierz Lipka Bozena Mierzejewska Justyna Milewska-Bobula Bogumi?a Smorczewska-Kiljan Anna Jahnz-Rózyk Karina Dzierzanowska Danuta Madaliński Kazimierz Litwińska Bogumi?a |
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Institution: | Department of Virology, National Institute of Public Heath, National Institute of Hygiene, Warsaw, Poland. kpancer@pzh.gov.pl |
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Abstract: | Respiratory Syncytial Virus (RSV) is one of the most common causes of lower respiratory tract infections in young children, immunocompromised patients (children and adults), patients with chronic respiratory diseases and elderly people. Reinfections occur throughout the life, but the severity of disease decreased with subsequent infection. The aim of this study was to analyze the frequency of RSV infections in two selected subpopulations: young children (below 5 y.) and adults with chronic respiratory diseases (25-87 y.). Nasopharyngeal swabs (334) collected from October 2008 to March 2010 were examined. The presence of RSV genome was determined by RT-PCR and the presence of RSV antigen by quick immunochromatographic test. Positive results of RT-PCR were found in 45.2% of all swabs: 48.6% samples in 2008; 41.5% in 2009; 50.8% in 2010. The highest frequency of RSV-positive samples was in fall-winter months, but differences in RSV epidemic seasons were found. In the first season (2008-2009) an increased number of RSV infections was observed from November 2008, but in the second season--from January 2010. Generally, the frequency of RSV-positive RT-PCR among children was 53%, among adults 25%. The highest difference was observed in the first three-month period of 2010. RT-PCR positive samples were found in 68.5% of children and 5.9% of adults. However, the RSV antigen was found in 44.4% of samples collected from adults in this period. Our results indicate that the contribution of RSV infections during epidemic season of respiratory tract infections in Poland was really high among children and adults. |
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