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乳酸菌酸胁迫反应机制研究进展
引用本文:乌日娜,武俊瑞,孟和,张和平. 乳酸菌酸胁迫反应机制研究进展[J]. 微生物学杂志, 2007, 27(2): 62-66
作者姓名:乌日娜  武俊瑞  孟和  张和平
作者单位:1. 内蒙古农业大学,教育部乳品生物技术与工程重点实验室,内蒙古,呼和浩特,010018
2. 沈阳农业大学,食品学院,辽宁,沈阳,110161
3. 上海交通大学,农业与生物技术学院,上海,201101
摘    要:
乳酸菌可发酵糖类产生乳酸,并广泛应用于食品、药物和饲料等工业。由于有机酸的积累,乳酸菌大部分的生长代谢都在低pH的酸性环境中进行,具有酸胁迫反应。pH的自我平衡、ATR反应机制、对大分子的保护和修复作用及细胞膜的变化等是乳酸菌酸胁迫反应的主要机制,其中,pH自我平衡包括F0F1-ATPase质子泵、精氨酸脱氨酶途径(ADI)和谷氨酸脱羧酶途径(GAD)等。由此可见,乳酸菌酸胁迫反应机制涉及到基因和蛋白的表达调控等,是非常复杂的网络调控体系。

关 键 词:乳酸菌  酸胁迫  pH的自我平衡  ATR反应机制  大分子的保护和修复  细胞膜
文章编号:1005-7021(2007)02-0062-05
修稿时间:2006-07-20

Acid Intimidation Responses of Lactic Acid Bacteria
WU Ri-na,WU Jun-rui,MENG He,ZHANG He-ping. Acid Intimidation Responses of Lactic Acid Bacteria[J]. Journal of Microbiology, 2007, 27(2): 62-66
Authors:WU Ri-na  WU Jun-rui  MENG He  ZHANG He-ping
Abstract:
Lactic acid bacteria (LAB) could ferment sugars to produce lactic acid and widely used in food, medicine, forage, and other industries. Since the accumulation of organic acids, the greater part of their growth metabolism are carried out in acid conditions of low pH and possess intimidation responses. pH homeostasis, ATR, protection and repair of macromolecules and the change of cell membrane and others are major mechanisms of LAB against the acid intimidation responses. Among them, pH homeostasis includes F0F1-ATPase proton pump, ADI and GAD pathway and so on. It is therefore clear that the acid intimidation responses mechanism of LAB is a very complicated network regulation system involves the expression of genes and proteins regulation.
Keywords:lactic acid bacteria  acid intimidation responses  pH homeostasis  ATR  protection and repair of macromolecules  cell membrane
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