| 白念珠菌凋亡诱导研究进展 |
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| 引用本文： | 施高翔,严园园,邵菁,汪天明,汪长中.白念珠菌凋亡诱导研究进展[J].微生物学通报,2014,41(2):376-383. |
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| 作者姓名： | 施高翔 严园园 邵菁 汪天明 汪长中 |
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| 作者单位： | 安徽中医学院 中西医结合临床学院 安徽 合肥 230038;安徽中医学院 中西医结合临床学院 安徽 合肥 230038;安徽中医学院 中西医结合临床学院 安徽 合肥 230038;安徽中医学院 中西医结合临床学院 安徽 合肥 230038;安徽中医学院 中西医结合临床学院 安徽 合肥 230038 |
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| 基金项目： | 国家自然科学基金项目(No. 81073127)；安徽省自然科学基金项目(No. 090413092)；安徽省高校省级自然科学研究重点项目(No. KJ2010A220) |
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| 摘 要： | 近年来,白念珠菌为主的真菌感染病例日渐增多,新型抗真菌药物研发成为热点。在原有抗真菌机制的基础上,通过诱导凋亡抗真菌成为目前探寻抗真菌药物作用机制的一个新趋向。本文对目前国内外关于药物诱导白念珠菌凋亡研究做一综述。
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| 关 键 词： | 白念珠菌，凋亡，药物诱导 |
Advances in apoptosis induction in Candida albicans |
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| SHI Gao-Xiang,YAN Yuan-Yuan,SHAO Jing,WANG Tian-Ming and WANG Chang-Zhong.Advances in apoptosis induction in Candida albicans[J].Microbiology,2014,41(2):376-383. |
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| Authors: | SHI Gao-Xiang YAN Yuan-Yuan SHAO Jing WANG Tian-Ming and WANG Chang-Zhong |
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| Institution: | School of Integrated Traditional Chinese & Western Medicine, Anhui University of Traditional Chinese Medicine, Hefei, Anhui 230038, China;School of Integrated Traditional Chinese & Western Medicine, Anhui University of Traditional Chinese Medicine, Hefei, Anhui 230038, China;School of Integrated Traditional Chinese & Western Medicine, Anhui University of Traditional Chinese Medicine, Hefei, Anhui 230038, China;School of Integrated Traditional Chinese & Western Medicine, Anhui University of Traditional Chinese Medicine, Hefei, Anhui 230038, China;School of Integrated Traditional Chinese & Western Medicine, Anhui University of Traditional Chinese Medicine, Hefei, Anhui 230038, China |
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| Abstract: | In recent years, fungal infections caused by Candida albicans are increasing, and the development of novel antifungal drugs becomes a hotspot. On basis of antifungal mechanism, the induction of fungus apoptosis has become a new trend for the search of antifungal agents. In this paper, we review comprehensively the drug-induced apoptosis in C. albicans. |
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| Keywords: | Candida albicans Apoptosis Drug induction |
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