Synthesis of the mating factor of Saccharomyces cerevisiae and its truncated peptides : the structure-activity relationship. |
| |
| Authors: | Y Masui N Chino S Sakakibara T Tanaka T Murakami H Kita |
| |
| Affiliation: | 1. The Peptide Institute, Protein Research Foundation Minoh, Osaka 562, Japan;2. Central Research Institute, Suntory Ltd. Shimamoto-cho, Mishima-gun, Osaka 618, Japan |
| |
| Abstract: | The mating factor of Saccharomyces cerevisiae, Trp-His-Trp-Leu-Gln-Leu-Lys-Pro-Gly-Gln-Pro-Met-Tyr, has been synthesized to confirm the structure of the natural mating factor. The tridecapeptide has the same biological activity as the natural mating factor. From the studies on the biological activity of its truncated peptide synthesized the minimum sequence of the peptide require for the mating factor was deduced to be as His-Trp-Leu-Gln-Leu-Lys-Pro-Gly-Gln. |
| |
| Keywords: | Address correspondence to G.W.L. |
| 本文献已被 ScienceDirect 等数据库收录！ |
