DNA cleavage activities of (-)-epigallocatechin, (-)-epicatechin, (+)-catechin, and (-)-epigallocatechin gallate with various kinds of metal ions |
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| Authors: | Hayakawa F Kimura T Hoshino N Ando T |
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| Institution: | Department of Life Style Studies, School of Human Cultures, The University of Shiga Prefecture, Japan. |
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| Abstract: | The DNA cleavage activities of (+)-catechin (C), (-)-epicatechin (EC), (-)-epigallocatechin (EGC), and (-)-epigallocatechin gallate (EGCg) were examined with 16 different metal ions. Cu(2+) with all the catechins facilitated DNA cleavage, while Ag+ with EGC and EC showed a strong repressive effect. The other metal ions examined showed little effect. |
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