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骨髓间充质干细胞及其临床应用研究进展
引用本文:韩京,冉新泽,艾国平,粟永萍. 骨髓间充质干细胞及其临床应用研究进展[J]. 现代生物医学进展, 2007, 7(12): 1890-1892,1898
作者姓名:韩京  冉新泽  艾国平  粟永萍
作者单位:第三军医大学预防医学院全军复合伤研究所,创伤、烧伤与复合伤国家重点实验室,重庆,400038
基金项目:国家自然科学基金;国家重点基础研究发展计划(973计划)
摘    要:骨髓间充质干细胞因具有容易获得、容易体外培养增殖、长期培养的过程中始终保持多向分化的潜能、抗原性小、组织修复能力强等特征,使之成为干细胞研究领域的热点和前沿,并被认为是最有前途的组织工程种子细胞之一。以干细胞工程为代表的现代组织工程学为组织器官的修复与替代提供了一个崭新的领域,并将此领域扩展到细胞替代治疗、支持造血、基因治疗等更多方面。

关 键 词:骨髓间充质干细胞  组织工程  创伤修复
文章编号:1673-6273(2007)12-1890-03
修稿时间:2007-05-282007-07-30

Advances on Bone Mesenchymal Stem Cells in Clinical Application
HAN Jing,RAN Xin-ze,AI Guo-ping,SU Yong-ping. Advances on Bone Mesenchymal Stem Cells in Clinical Application[J]. Progress in Modern Biomedicine, 2007, 7(12): 1890-1892,1898
Authors:HAN Jing  RAN Xin-ze  AI Guo-ping  SU Yong-ping
Affiliation:The National Key Laboratory for Trauma, Adustum and Combined Injury, the Research Institute of Combined Injury, Preventative Medicine College ,the Third Military Medical University, Chongqing 400038, China
Abstract:Bone mesenchymal stem cells(MSCs) has become the hot spot and front edge in the research of stem cells because of their advantages such as easy to be acquired and cultured in vitro,maintaining multi-differention potentiality even after long-term culture, negligible antigenicity and strong tissue repair capacity and so on.It has been also considered as one of the most promising seed cells for bone tissue engineering.As a representative for the modern tissue engineering,stem cell engineering provides a new field of inquiry for the repair or replacement of tissues and organs,and expands to many other fields,including cell replacement therapy,hematopoiesis support and gene therapy.
Keywords:Bone mesenchymal stem cells  Tissue engineering  Repairment in trauma
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