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Cytotoxic and antiprotozoal activity of flavonoids from Lonchocarpus spp.
Authors:R Borges-Argez  L Balnbury  A Flowers  A Gimnez-Turba  G Ruiz  PG Waterman  LM Pea-Rodríguez
Institution:Centro de Investigación Científica de Yucatán, Calle 43 No 130 Chuburná, Mérida, Yucatán, México.
Abstract:A number of flavonoids isolated from Lonchocarpus spp. were evaluated for their antiprotozoal and cytotoxic activity. Flavone 6 and chalcone 7 were found to be the most active against Leishmania parasites and against cell cultures of Leukemia P388DI and adenocarcinoma prostate PC-3.
Keywords:Flavonoids  Flavone  Chalcone  Lonchocarpus  Antiprotozoal activity  Cytotoxic activity
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