|
|||||
|
|
Mechanisms of Microsporidial Cell Division: Ultrastructural Study on Encephalitozoon hellem |
|
| Authors: | Elisa Bigliardi Maria Giovanna Riparbelli Maria Gloria Selmi Paolo Lanzarini Silvia Corona Simonetta Gatti Massimo Scaglia Luciano Sacchi |
| Affiliation: | Department of Evolutionary Biology, University. Via Mattioli 4, 53100 Siena, Italy;Electron Microscopy Lab., Inst. Infect. Diseases, University-IRCCS S. Matteo. 27100 Pavia, Italy;Parasitology Lab., Virology Service, IRCCS S. Matteo, 27100 Pavia, Italy;Infectious Diseases Research Labs., University-IRCCS S. Matteo, 27100 Pavia, Italy;Department of Animal Biology. University. 27100 Pavia. Italy |
| Abstract: | The mitotic process in microsporidian Encephalitozoon hellem. a known human pathogen, has been studied with the aim of elucidating some ultrastructural aspects of its nuclear division. The presence of a nuclear spindle, of electrondense spindle plaques associated with the nuclear envelope and of cytoplasmic double walled vesicles are reported. We suggest that these electrondense spindle plaques serve as foci for intranuclear and cytoplasmic microtubule arrangements, similar to the microtubule organizing centers within the centrosomes of animal cells. The extent to which the microsporidial division process is comparable with that of more familiar eukaryotes such as yeast cells is discussed. |
| Keywords: | Double walled vesicles electrondense spindle plaques Encephalitozoon hellem Microsporidia microtubules |