Synthesis and absolute configuration of MQ-A3 [1-(14'-methylhexadecanoyl) pyrrolidine], a novel aliphatic pyrrolidine amide from the tropical convolvulaceous species |
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Authors: | Yajima A Yabuta G |
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Affiliation: | Department of Fermentation Science, Faculty of Applied Biological Science, Tokyo University of Agriculture, Japan. |
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Abstract: | A novel pyrrolidine amide (MQ-A3) isolated from the tropical convolvulaceous species was synthesized in 5 steps by starting from commercially available 12-bromododecanol and (S)-2-methylbutylbromide. The absolute configuration of the natural product was confirmed by a comparison of the specific rotation values. |
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