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Translational defects in a mutant deficient in YajL, the bacterial homolog of the parkinsonism-associated protein DJ-1
Authors:Kthiri Fatoum  Gautier Valérie  Le Hai-Tuong  Prère Marie-Françoise  Fayet Olivier  Malki Abderrahim  Landoulsi Ahmed  Richarme Gilbert
Affiliation:Stress Molecules, Institut Jacques Monod, Université Paris 7, 2 Place Jussieu, Paris, France.
Abstract:
We report here that YajL is associated with ribosomes and interacts with many ribosomal proteins and that a yajL mutant of Escherichia coli displays decreased translation accuracy, as well as increased dissociation of 70S ribosomes into 50S and 30S subunits after oxidative stress.
Keywords:
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