Translational defects in a mutant deficient in YajL, the bacterial homolog of the parkinsonism-associated protein DJ-1 |
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Authors: | Kthiri Fatoum Gautier Valérie Le Hai-Tuong Prère Marie-Françoise Fayet Olivier Malki Abderrahim Landoulsi Ahmed Richarme Gilbert |
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Affiliation: | Stress Molecules, Institut Jacques Monod, Université Paris 7, 2 Place Jussieu, Paris, France. |
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Abstract: | ![]() We report here that YajL is associated with ribosomes and interacts with many ribosomal proteins and that a yajL mutant of Escherichia coli displays decreased translation accuracy, as well as increased dissociation of 70S ribosomes into 50S and 30S subunits after oxidative stress. |
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