Earlier accumulation of calcium, phosphorus, and magnesium in the coronary artery in comparison with the ascending aorta, aortic valve, and mitral valve |
| |
| Authors: | Yoshiyuki Tohno Setsuko Tohno Pasuk Mahakkanukrauh Cho Azuma Yumi Moriwake Nutcharin Ongkana Tsukasa Kumai Takeshi Minami Hirohisa Maruyama |
| |
| Institution: | (1) Laboratory of Cell Biology, Department of Anatomy, Nara Medical University School of Medicine, Kashihara, 634-8521 Nara, Japan;(2) Department of Orthopaedic Surgery, Nara Medical University School of Medicine, Kashihara, 634-8521 Nara, Japan;(3) Department of Anatomy, Faculty of Medicine, Chiang Mai University, 50200 Chiang Mai, Thailand;(4) Laboratory of Environmental Biology, Department of Life Science, Faculty of Science and Engineering, Kinki University, Higashi-Osaka, 577-8502 Osaka, Japan;(5) Hyogo Nutrition Vocational College, Nishinomiya, 662-0833 Hyogo, Japan |
| |
| Abstract: | To explore reasons for a high accumulation of Ca and P occurring in the coronary artery of Thai with aging, the authors investigated
age-related changes of elements in the coronary artery, ascending aorta near the heart, and cardiac valves in single individuals,
and the relationships in the elements between the coronary artery and either the ascending aorta or cardiac valves. After
an ordinary dissection by medical students at Chiang Mai University was finished, the anterior descending arteries of the
left coronary artery, ascending aortas, mitral valves, and aortic valves were resected from the subjects. The subjects consisted
of 17 men and 9 women, ranging in age from 46 to 76 yr. The element content was analyzed by inductively coupled plasma-atomic
emission spectrometry. The average content of Ca and P was the highest in the coronary artery and decreased in the order aortic
valve, ascending aorta, and mitral valve. The Ca, P, and Mg content increased in the coronary artery in the fifties and in
the ascending aorta, aortic valve, and mitral valve in the sixties. It should be noted that the accumulation of Ca, P, and
Mg occurred earlier in the coronary artery than in the ascending aorta, aortic valve, and mitral valve. It was found that
with respect to the Ca, P, Mg, and Na contents, the coronary artery correlated well with both the aortic valve and ascending
aorta, especially with the aortic valve, but it did not correlate with the mitral valves. This finding suggests that the accumulation
of Ca, P, Mg, and Na occurs in the coronary artery together with the aortic valve and ascending aorta, but not together with
the mitral valve. Because regarding the accumulation of Ca, P, and Mg, the ascending aorta and aortic valve are preceded by
the coronary artery, it is unlikely that the accumulation of Ca, P, and Mg spreads from the ascending aorta or aortic valve
to the coronary artery. |
| |
| Keywords: | Coronary artery aorta aortic valve mitral valve calcium phosphorus magnesium |
| 本文献已被 PubMed SpringerLink 等数据库收录！ |
|
