Drastic changes in the peptidoglycan composition of penicillin resistant laboratory mutants of Streptococcus pneumoniae |
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| Authors: | AnatolySeverin Maria Vitoria VazPato Agnes Marie SáFigueiredo AlexanderTomasz |
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| Institution: | National Institute of Bioscience and Human-Technology (NIBH), 1, Higashi, Tsukuba, Ibaraki 305, Japan |
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| Abstract: | Abstract Rhodococcus erythropolis strain S1 uses the gentisate pathway to metabolize salicylate and m -hydroxybenzoate and the protocatechuate pathway to degrade p -hydroxybenzoate. m -Hydroxybenzoate 6-hydroxylase was induced by growth on m -hydroxybenzoate or gentisate, and salicylate 5-hydroxylase only by growth on salicylate. p -Hydroxybenzoate 3-hydroxylase could be induced only by growth on p -hydroxybenzoate. m -Hydroxybenzoate or p -hydroxybenzoate could repress the induction of salicylate 5-hydroxylase. Maleylpyruvate isomerase in the gentisate pathway did not require reduced glutathione. |
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| Keywords: | Rhodococcus erythropolis Salicylate 5-hydroxylase m-Hydroxybenzoate 6-hydroxylase p-Hydroxybenzoate 3-hydroxylase Catabolite repression |
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