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Mitochondrial mutagenesis in Saccharomyces cerevisiae V. Ethyl methanesulfonate
Authors:R. Polakowska  A. Putrament
Affiliation:Department of Genetics, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Rakowiecka 36, 02-532 Warsaw, Poland
Abstract:Mitochondrial genomes are more sensitive to the lethal action of EMS than are nuclear genomes of S. cerevisiae. EMS induces efficiently only some types of mutation in nuclear genomes of yeast, and probably the same is true for induction of mutations non-lethal to the mitochondrial genomes.
Keywords:DEN  diethylnitrosamine  DMN  dimethylnitrosamine  mitDNA  mitochondrial DNA  EMS  ethyl methanesulfonate  MMS  methyl methanesulfonate  MNNG
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