The synthesis of two repeating units of Haemophilus influenzae type a capsular antigen |
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Authors: | B Grzeszczyk A Banaszek A Zamojski |
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Affiliation: | Institute of Organic Chemistry, Polish Academy of Sciences, Warszawa. |
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Abstract: | The repeating units 2-O-beta-D-glucopyranosyl-L-ribitol 4'- and 1-phosphate of Haemophilus influenzae type a capsular antigen have been synthesised by condensation of an alpha-D-glucopyranosyl bromide derivative with 5-O-allyl-1,2,3-tri-O-benzyl-D-ribitol followed by selective deprotection of HO-4' or HO-1, phosphorylation, and removal of the blocking groups. |
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