Hamster oocyte maturation : Inhibition by follicular components |
| |
Authors: | RBL Gwatkin OF Andersen |
| |
Institution: | Department of Reproductive and Cell Biology Merck Institute for Therapeutic Research Rahway, New Jersey 07065, USA |
| |
Abstract: | When prevulatory hamster follicles were cultured , the oocytes within them remained at the germinal vesicle stage. This maturation arrest was partly overcome by washing the follicles before cultivation or by the addition of LH to the medium. LH-reversible oocyte arrest was also induced in isolated oocytes by culturing them either with the cumulus oophorus or with hamster follicular fluid was not species-specific, inhibitory effect of follicular fluid was not species-specific, since an LH-reversible inhibition was also produced by follicular fluid of bovine origin. Evidence is presented indicating that the inhibition is due to a heat labile peptide with a molecular weight between 10 0 and 10,000. LH may induce oocyte maturation by acting on the oocyte so that it no longer responds to the inhibitor. |
| |
Keywords: | |
本文献已被 ScienceDirect 等数据库收录! |
|