Sapatoxins,aliphatic ester tigliane diterpenes from Sapium indicum |
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| Authors: | S.E. Taylor M.A. Gafur A.K. Choudhury F.J. Evans |
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| Affiliation: | 1. B.C.S.I.R. Laboratories, P.O. Bayazied Bostami, Chittagong, Bangladesh |
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| Abstract: | From the unripe fruits of Sapium indicum, three aliphatic esters of the tigliane nucleus were isolated. These compounds were derivatives of 4-deoxyphorbol. Sapatoxin A was identified as 12-O-[n-deca-2,4,6-trienoyl]-4-deoxyphorbol-13-acetate, B as 12-O-[n-deca-2,4,6-trienoyl]-4-deoxy-5-hydroxyphorbol-13-acetate and C as 12-O-[n-deca-2,4,6-trienoyl]-4,20-dideoxy-5-hydroxyphorbol-13-acetate, by spectroscopic analysis and hydrolysis reactions. |
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| Keywords: | Euphorbiaceae fruits aliphatic esters 4-deoxyphorbol 4-deoxy-5-hydroxyphorbol 4,20-dideoxy-5-hydroxyphorbol. |
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