Interactions between GPI-anchored proteins and membrane lipids |
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Authors: | Brown D A |
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Affiliation: | Department of Biochemistry and Cell Biology, SUNY at Stony Brook, Stony Brook, NY 11794, USA. |
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Abstract: | Proteins anchored in membranes by glycosylphosphatidylinositol (GPI) are widely distributed, but the function of this unusual anchor is a puzzle. Recent evidence shows that these proteins can associate with membrane lipids in special ways. One function of GPI anchorage may be to allow proteins to interact with specialized membrane domains. |
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