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Involvement of two-component system CBO0366/CBO0365 in the cold shock response and growth of group I (proteolytic) Clostridium botulinum ATCC 3502 at low temperatures
Authors:Lindström Miia  Dahlsten Elias  Söderholm Henna  Selby Katja  Somervuo Panu  Heap John T  Minton Nigel P  Korkeala Hannu
Institution:Department of Food Hygiene and Environmental Health, University of Helsinki, Helsinki, Finland. miia.lindstrom@helsinki.fi
Abstract:The role of the two-component system (TCS) CBO0366/CBO0365 in the cold shock response and growth of the mesophilic Clostridium botulinum ATCC 3502 at 15°C was demonstrated by induced expression of the TCS genes upon cold shock and impaired growth of the TCS mutants at 15°C.
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