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Contribution of Val/Ile87 residue in the extracellular domain in agonist-induced current responses of the human and rat P2X7 receptors |
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| Authors: | Caseley Emily A Muench Stephen P Jiang Lin-Hua |
| Institution: | 1.Leeds Institute of Rheumatic and Musculoskeletal Medicine, St James’s University Hospital, Faculty of Medicine and Health, Leeds, UK ;2.School of Biomedical Sciences, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 JT, UK ; |
| Abstract: | Purinergic Signalling - The P2X7 receptor (P2X7R) is an ATP-gated cation channel with a critical role in many physiological and pathological processes, and shows prominent functional differences... |
| Keywords: | P2X7 receptor Species difference Agonist-induced currents Whole-cell recording |
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