刺五加提取物对早期断奶仔猪生长性能和抗氧化能力的影响(英文)

为了研究刺五加提取物(ASE)替代抗生素降低仔猪早期断奶应激的效果及其作用机制.刺五加提取物多糖、黄酮和有机酸含量分别为2.94,0.19和1.04%;试验选用96头体重相近的21日龄杜×长×大断奶仔猪,按体重和性别随机分为3个处理,每个处理4个重复,分别饲喂基础日粮、添加ASE日粮(1 g/kg)和添加抗生素日粮(0.04%杆菌肽锌+0.03%咔吧氧).试验期为14 d,观察仔猪生长性能,测定7和14 d血清抗氧化指标等的变化.与基础日粮组相比,ASE和抗生素分别提高了仔猪日增重(ADG)16.81(P＞0.05)和24.66%(P＜0.05),均显著降低了料肉比(F/G)(P＜0.05);与抗生素组差异不显著.ASE和抗生素均可提高血清SOD水平;但是,在抗生素组中,第14 d仔猪血清SOD有降低的趋势(从147.96±15.88 U/mL降低至125.68±14.26U/mL).ASE有提高断奶后第7和14 d血清GSH含量的趋势(P=0.235和0.211),并极显著降低了7和14 d血清MDA水平(P＜0.05).结果表明,ASE可促进仔猪生长,提高机体抗氧化能力,在一定程度上可以替代抗生素.

Effects of Acanthopanax senticosus Extract on Growth Performance and Anti-oxidative Capacity in Weaned Piglet

This study was conducted to investigate the effect of Acanthopanax senticosus extract(XSE)on the growth performance and antioxidant capacity of weaned piglets.Dried AS herb was decocted in boiling distilled water(200 g/L)for 2 h.The decoction products were filtered and lypholized.The yield of extract was about 25%(w/w),with total polysaccherides,flavone and organic acids 2.94,0.19 and 1.04%,respectively.Ninety-six Duroc×Landrace×Yorkshire piglets weaned at 21 days of age(BW=5.64±0.48 kg)were randomly assigned to one of 3 treatments with 4 replicates each and fed a basal diet(BD),BD+ASE(1g/kg),and BD+antibiotics(10% bacitmein zinc 400 nag+15%carbadox 300 mg)for 14 days.Blood samples were collected on d7 and 14.ADG in the ASE group(216.80 g/d)and antibiotics group(231.38 g/d)were 16.81(P＞0.05)and 24.66%(P＜0.05)higher than the control group,and gain-feed ratio was improved by 18.18 and 21.39%(P＜0.05),respectively.However,there was no difference in growth performance between the ASE and antibiotic group(P＞0.05).Compared to the control group,both ASE and antibiotics increased Cu-Zn superoxide dismutase(SOD)activity on d 7 and 14(P＜0.05).SoD activity decreased from 147.96±15.88 to 125.68±14.26 in the antibiotics group(P＜0.05),while increased in the ASE group(from 132.37±7.64 to 135.44±12.68).Malondialdehyde in the ASE group significantly decreased by 20.00 and 30.46%(P＜0.05)on d 7 and 14,respectively.Glutathione also had an increasing trend in the ASE group on d 7 and 14(P=0.235 and 0.211,respectively).In addition,ASE influenced serum IgG on d 14(P＜0.05).These findings indicted that ASE could alleviate weaning stress by improving antioxidant enzymatic system effectively in piglets.