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Role of the eIF4E binding protein 4E‐BP1 in regulation of the sensitivity of human pancreatic cancer cells to TRAIL and celastrol‐induced apoptosis
Authors:Reka Chakravarthy  Michael J. Clemens  Grisha Pirianov  Nectarios Perdios  Satvinder Mudan  Judith E. Cartwright  Androulla Elia
Affiliation:1. Translational Control Group, Division of Biomedical Sciences, St George's, University of London, , London, SW17 0RE UK;2. Department of Biochemistry and Molecular Biology, School of Life Sciences, University of Sussex, , UK;3. Division of Clinical Sciences, St George's, University of London, , London, SW17 0RE UK;4. Department of Surgery, Royal Marsden Hospital, , London, SW3 6JJ UK;5. Reproductive and Cardiovascular Disease Research Group, Division of Biomedical Sciences, St George's, University of London, , London, SW17 0RE UK
Abstract:
Keywords:anti‐cancer  protein synthesis  therapeutic  triterpene  tumour necrosis factor α  ‐related apoptosis‐inducing ligand (TRAIL)
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