Mutagenesis of the fusion peptide-like domain of hepatitis C virus E1 glycoprotein: involvement in cell fusion and virus entry |
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| Authors: | Hsiao-Fen Li Chia-Hsuan Huang Li-Shuang Ai Chin-Kai Chuang Steve SL Chen |
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| Institution: | (1) Institute of Biomedical Sciences, Academia Sinica, 11529 Taipei, Taiwan;(2) Division of Biotechnology, Animal Technology Institute Taiwan, 35053 Miaoli, Taiwan |
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| Abstract: | Background Envelope (E) glycoprotein E2 of the hepatitis C virus (HCV) mediates binding of the virus to target cell receptors. Nevertheless,
the precise role of E1 in viral entry remains elusive. |
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